Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

11 papers

NM_002447.4

p.Q523R

c.1568A>G

Surrounding Variants

1 paper

NM_002447.4

p.Q523*

c.1567C>T

1 paper

NM_002447.4

p.G524C

c.1570G>T

1 paper

NM_002447.4

p.G524A

c.1571G>C

1 paper

NM_002447.4

p.P525H

c.1574C>A

1 paper

NM_002447.4

p.C527*

c.1581C>A

1 paper

NM_002447.4

p.T532A

c.1594A>G

1 paper

NM_002447.4

p.G534A

c.1601G>C

1 paper

NM_002447.4

p.R535C

c.1603C>T

1 paper

NM_002447.4

p.H541D

c.1621C>G

1 paper

NM_002447.4

p.G544C

c.1630G>T

1 paper

NM_002447.4

p.G544A

c.1631G>C

1 paper

NM_002447.4

p.G544G

c.1632C>A