Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.A462G

c.1385C>G

Surrounding Variants

1 paper

NM_002447.4

p.A462S

c.1384G>T

1 paper

NM_002447.4

p.A462T

c.1384G>A

1 paper

NM_002447.4

p.G465D

c.1394G>A

1 paper

NM_002447.4

p.R455H

c.1364G>A

2 papers

NM_002447.4

p.R455C

c.1363C>T

1 paper

NM_002447.4

p.R470C

c.1408C>T

2 papers

NM_002447.4

p.R470H

c.1409G>A

2 papers

NM_002447.4

p.Q473_V474Splc

c.1419+1G>A

1 paper

NM_002447.4

p.A450T

c.1348G>A

1 paper

NM_002447.4

p.Q447*

c.1339C>T

1 paper

NM_002447.4

p.G444A

c.1331G>C

1 paper

NM_002447.4

p.L442L

c.1326G>C