Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.N440K

c.1320T>A

Surrounding Variants

1 paper

NM_002447.4

p.N440K

c.1320T>G

4 papers

NM_002447.4

p.N440S

c.1319A>G

1 paper

NM_002447.4

p.G441A

c.1322G>C

1 paper

NM_002447.4

p.L442L

c.1326G>C

1 paper

NM_002447.4

p.G444A

c.1331G>C

3 papers

NM_002447.4

p.S434L

c.1301C>T

1 paper

NM_002447.4

p.Q447*

c.1339C>T

1 paper

NM_002447.4

p.S432S

c.1296C>T

1 paper

NM_002447.4

p.S432C

c.1294A>T

1 paper

NM_002447.4

p.A450T

c.1348G>A

2 papers

NM_002447.4

p.R455C

c.1363C>T

1 paper

NM_002447.4

p.P426H

c.1277C>A