Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.C386R

c.1156T>C

Surrounding Variants

1 paper

NM_002447.4

p.C385Y

c.1154G>A

1 paper

NM_002447.4

p.E387D

c.1161A>T

1 paper

NM_002447.4

p.G381A

c.1142G>C

4 papers

NM_002447.4

p.R396*

c.1186C>T

1 paper

NM_002447.4

p.L374V

c.1120C>G

2 papers

NM_002447.4

p.S403L

c.1208C>T

1 paper

NM_002447.4

p.A368G

c.1103C>G

1 paper

NM_002447.4

p.A368T

c.1102G>A

1 paper

NM_002447.4

p.C367G

c.1099T>G

1 paper

NM_002447.4

p.V365I

c.1093G>A

1 paper

NM_002447.4

p.N409S

c.1226A>G

2 papers

NM_002447.4

p.P410L

c.1229C>T