Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_002447.4

p.R322Q

c.965G>A

Surrounding Variants

1 paper

NM_002447.4

p.V323fs

c.967_968fs

1 paper

NM_002447.4

p.L321P

c.962T>C

2 papers

NM_002447.4

p.A327T

c.979G>A

1 paper

NM_002447.4

p.G315R

c.943G>C

1 paper

NM_002447.4

p.G315R

c.943G>A

1 paper

NM_002447.4

p.G330C

c.988G>T

1 paper

NM_002447.4

p.G330A

c.989G>C

1 paper

NM_002447.4

p.E313V

c.938A>T

1 paper

NM_002447.4

p.E313K

c.937G>A

1 paper

NM_002447.4

p.A311fs

c.931_932fs

1 paper

NM_002447.4

p.L333R

c.998T>G

1 paper

NM_002447.4

p.A311insFs

c.931dupG