Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.A285G

c.854C>G

Surrounding Variants

2 papers

NM_002447.4

p.A285T

c.853G>A

2 papers

NM_002447.4

p.T278_R279delFs

c.834_835delGT

1 paper

NM_002447.4

p.R279fs

c.835_836fs

1 paper

NM_002447.4

p.T278fs

c.832_833fs

1 paper

NM_002447.4

p.H277Q

c.831C>G

1 paper

NM_002447.4

p.H277Q

c.831C>A

1 paper

NM_002447.4

p.L296P

c.887T>C

1 paper

NM_002447.4

p.D299N

c.895G>A

1 paper

NM_002447.4

p.D271V

c.812A>T

1 paper

NM_002447.4

p.T270A

c.808A>G

1 paper

NM_002447.4

p.R301insFs

c.901_902insC

2 papers

NM_002447.4

p.R306H

c.917G>A