Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.Y249H

c.745T>C

Surrounding Variants

1 paper

NM_002447.4

p.V250M

c.748G>A

1 paper

NM_002447.4

p.T255A

c.763A>G

2 papers

NM_002447.4

p.P239S

c.715C>T

1 paper

NM_002447.4

p.L235W

c.704T>G

1 paper

NM_002447.4

p.L235S

c.704T>C

1 paper

NM_002447.4

p.L235*

c.704T>A

1 paper

NM_002447.4

p.A234A

c.702G>T

1 paper

NM_002447.4

p.A234A

c.702G>A

1 paper

NM_002447.4

p.V233fs

c.697_698fs

1 paper

NM_002447.4

p.F232insFs

c.696dupT

1 paper

NM_002447.4

p.V233fs

c.697_698fs

1 paper

NM_002447.4

p.F232F

c.696T>C