Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.D173H

c.517G>C

Surrounding Variants

1 paper

NM_002447.4

p.D173Y

c.517G>T

1 paper

NM_002447.4

p.D173N

c.517G>A

1 paper

NM_002447.4

p.D172D

c.516T>C

1 paper

NM_002447.4

p.D172E

c.516T>A

1 paper

NM_002447.4

p.D173D

c.519C>T

1 paper

NM_002447.4

p.P171_D172ins2

c.513_514ins6

1 paper

NM_002447.4

p.P171_D172ins1

c.513_514insTGA

1 paper

NM_002447.4

p.C174C

c.522C>T

1 paper

NM_002447.4

p.P171L

c.512C>T

1 paper

NM_002447.4

p.C174W

c.522C>G

1 paper

NM_002447.4

p.P171R

c.512C>G

1 paper

NM_002447.4

p.C174*

c.522C>A