Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.L148L

c.442C>T

Surrounding Variants

1 paper

NM_002447.4

p.L148I

c.442C>A

1 paper

NM_002447.4

p.E149*

c.445G>T

1 paper

NM_002447.4

p.E149Q

c.445G>C

1 paper

NM_002447.4

p.E149K

c.445G>A

1 paper

NM_002447.4

p.H146R

c.437A>G

1 paper

NM_002447.4

p.H146Y

c.436C>T

1 paper

NM_002447.4

p.H146N

c.436C>A

1 paper

NM_002447.4

p.P150P

c.450C>T

1 paper

NM_002447.4

p.P150P

c.450C>G

1 paper

NM_002447.4

p.P150P

c.450C>A

1 paper

NM_002447.4

p.C143G

c.427T>G

2 papers

NM_002447.4

p.C143R

c.427T>C