Varaico: Literature-Extracted Genetic Variants

MTBP

60 papers

RefSeq Summary

This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provide...

Pfam Domains

MTBP_Naa 1–270UCSCMDM2-binding

MTBP_midaa 294–632UCSCMDM2-binding

MTBP_Caa 636–894UCSCMDM2-binding

Gene Aliases

HGNC Name

MDM2 binding protein

HGNC Previous Names

MDM2 (mouse double minute 2)-binding protein, 104kD; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022045.5

p.S255R

c.765T>A

Surrounding Variants

1 paper

NM_022045.5

p.S255R

c.765T>G

1 paper

NM_022045.5

p.S255R

c.763A>C

1 paper

NM_022045.5

p.E258V

c.773A>T

1 paper

NM_022045.5

p.L261I

c.781T>A

1 paper

NM_022045.5

p.T265A

c.793A>G

1 paper

NM_022045.5

p.N268K

c.804T>A

1 paper

NM_022045.5

p.D313H

c.937G>C

2 papers

NM_022045.5

p.D313A

c.938A>C

1 paper

NM_022045.5

p.S320L

c.959C>T

1 paper

NM_022045.5

p.W246R

c.736T>A

1 paper

NM_022045.5

p.W246R

c.736T>C

1 paper

NM_022045.5

p.E237K

c.709G>A