Varaico: Literature-Extracted Genetic Variants

MTBP

60 papers

RefSeq Summary

This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provide...

Pfam Domains

MTBP_Naa 1–270UCSCMDM2-binding

MTBP_midaa 294–632UCSCMDM2-binding

MTBP_Caa 636–894UCSCMDM2-binding

Gene Aliases

HGNC Name

MDM2 binding protein

HGNC Previous Names

MDM2 (mouse double minute 2)-binding protein, 104kD; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022045.5

p.K627R

c.1880A>G

Surrounding Variants

1 paper

NM_022045.5

p.Q621Q

c.1863A>G

1 paper

NM_022045.5

p.P616R

c.1847C>G

1 paper

NM_022045.5

p.T611A

c.1831A>G

1 paper

NM_022045.5

p.K608R

c.1823A>G

1 paper

NM_022045.5

p.K604R

c.1811A>G

1 paper

NM_022045.5

p.K591R

c.1772A>G

1 paper

NM_022045.5

p.S579*

c.1736C>A

1 paper

NM_022045.5

p.S579*

c.1736C>G

1 paper

NM_022045.5

p.S579A

c.1735T>G

1 paper

NM_022045.5

p.T577A

c.1729A>G

1 paper

NM_022045.5

p.K630R

c.1889A>G

1 paper

NM_022045.5

p.V633D

c.1898T>A