Varaico: Literature-Extracted Genetic Variants

MTBP

60 papers

RefSeq Summary

This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provide...

Pfam Domains

MTBP_Naa 1–270UCSCMDM2-binding

MTBP_midaa 294–632UCSCMDM2-binding

MTBP_Caa 636–894UCSCMDM2-binding

Gene Aliases

HGNC Name

MDM2 binding protein

HGNC Previous Names

MDM2 (mouse double minute 2)-binding protein, 104kD; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022045.5

p.S738A

c.2212T>G

Surrounding Variants

2 papers

NM_022045.5

p.R736W

c.2206C>T

1 paper

NM_022045.5

p.G720E

c.2159G>A

1 paper

NM_022045.5

p.G720R

c.2158G>A

1 paper

NM_022045.5

p.G720R

c.2158G>C

1 paper

NM_022045.5

p.P718T

c.2152C>A

1 paper

NM_022045.5

p.S711L

c.2132C>T

2 papers

NM_022045.5

p.S707A

c.2119T>G

1 paper

NM_022045.5

p.T687A

c.2059A>G

1 paper

NM_022045.5

p.R684C

c.2050C>T

5 papers

NM_022045.5

p.L750F

c.2248C>T

1 paper

NM_022045.5

p.K752R

c.2255A>G

1 paper

NM_022045.5

p.S761A

c.2281T>G