Varaico: Literature-Extracted Genetic Variants

MTBP

60 papers

RefSeq Summary

This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provide...

Pfam Domains

MTBP_Naa 1–270UCSCMDM2-binding

MTBP_midaa 294–632UCSCMDM2-binding

MTBP_Caa 636–894UCSCMDM2-binding

Gene Aliases

HGNC Name

MDM2 binding protein

HGNC Previous Names

MDM2 (mouse double minute 2)-binding protein, 104kD; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_022045.5

p.S761A

c.2281T>G

Surrounding Variants

1 paper

NM_022045.5

p.S761F

c.2282C>T

1 paper

NM_022045.5

p.N768D

c.2302A>G

1 paper

NM_022045.5

p.K752R

c.2255A>G

5 papers

NM_022045.5

p.L750F

c.2248C>T

1 paper

NM_022045.5

p.V774V

c.2322G>C

1 paper

NM_022045.5

p.T781A

c.2341A>G

1 paper

NM_022045.5

p.R783Q

c.2348G>A

2 papers

NM_022045.5

p.T799A

c.2395A>G

1 paper

NM_022045.5

p.T804A

c.2410A>G

1 paper

NM_022045.5

p.S808A

c.2422T>G

1 paper

NM_022045.5

p.S827A

c.2479T>G

1 paper

NM_022045.5

p.H845Q

c.2535C>A