Varaico: Literature-Extracted Genetic Variants

MTIF2

53 papers

RefSeq Summary

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is...

Pfam Domains

GTP_EFTUaa 179–344UCSCElongation factor Tu GTP binding domain

EF-G_D2aa 354–434UCSCElongation factor G domain 2

IF-2aa 495–607UCSCTranslation-initiation factor 2

Gene Aliases

HGNC Name

mitochondrial translational initiation factor 2

HGNC Alias Symbol

IF-2mt

Papers

RefSeq ID

Protein change

DNA change

1–12 of 65 variants

6 papers

NM_002453.3

p.T59N

c.176C>A

4 papers

NM_002453.3

p.V556I

c.1666G>A

4 papers

NM_002453.3

p.V634L

c.1900G>T

4 papers

NM_002453.3

p.V634L

c.1900G>C

3 papers

NM_002453.3

p.F659C

c.1976T>G

1 paper

NM_002453.3

p.M1I

c.3G>A

1 paper

NM_002453.3

p.N2I

c.5A>T

1 paper

NM_002453.3

p.Q3*

c.7C>T

1 paper

NM_002453.3

p.R13*

c.37C>T

1 paper

NM_002453.3

p.F37L

c.109T>C

1 paper

NM_002453.3

p.F37L

c.111T>G

1 paper

NM_002453.3

p.F37L

c.111T>A