Varaico: Literature-Extracted Genetic Variants

MTIF2

53 papers

RefSeq Summary

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is...

Pfam Domains

GTP_EFTUaa 179–344UCSCElongation factor Tu GTP binding domain

EF-G_D2aa 354–434UCSCElongation factor G domain 2

IF-2aa 495–607UCSCTranslation-initiation factor 2

Gene Aliases

HGNC Name

mitochondrial translational initiation factor 2

HGNC Alias Symbol

IF-2mt

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002453.3

p.F37L

c.109T>C

Surrounding Variants

1 paper

NM_002453.3

p.F37L

c.111T>G

1 paper

NM_002453.3

p.F37L

c.111T>A

1 paper

NM_002453.3

p.S38fs

c.112_113fs

1 paper

NM_002453.3

p.S38delFs

c.113delG

1 paper

NM_002453.3

p.P54Q

c.161C>A

6 papers

NM_002453.3

p.T59N

c.176C>A

1 paper

NM_002453.3

p.A61T

c.181G>A

1 paper

NM_002453.3

p.R13*

c.37C>T

1 paper

NM_002453.3

p.Q3*

c.7C>T

1 paper

NM_002453.3

p.N2I

c.5A>T

1 paper

NM_002453.3

p.M1I

c.3G>A

1 paper

NM_002453.3

p.W94R

c.280T>C