Varaico: Literature-Extracted Genetic Variants

MX1

205 papers

RefSeq Summary

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagon...

Pfam Domains

Dynamin_Naa 73–249UCSCDynamin family

Dynamin_Maa 259–547UCSCDynamin central region

GEDaa 569–660UCSCDynamin GTPase effector domain

Gene Aliases

HGNC Name

MX dynamin like GTPase 1

HGNC Alias Symbols

IFI-78K; MxA; lncMX1-215

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002462.5

p.E138A

c.413A>C

Surrounding Variants

1 paper

NM_002462.5

p.V139L

c.415G>C

1 paper

NM_002462.5

p.S134L

c.401C>T

1 paper

NM_002462.5

p.A146D

c.437C>A

2 papers

NM_002462.5

p.T103T

c.309C>G

12 papers

NM_002462.5

p.T103A

c.307A>G

1 paper

NM_002462.5

p.P96S

c.286C>T

1 paper

NM_002462.5

p.L95P

c.284T>C

1 paper

NM_002462.5

p.L95delFs

c.284delT

1 paper

NM_002462.5

p.L90_S91insA

c.268_272ins3

1 paper

NM_002462.5

p.S85S

c.255C>G

2 papers

NM_002462.5

p.K83M

c.248A>T

1 paper

NM_002462.5

p.S81L

c.242C>T