Varaico: Literature-Extracted Genetic Variants

MX1

205 papers

RefSeq Summary

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagon...

Pfam Domains

Dynamin_Naa 73–249UCSCDynamin family

Dynamin_Maa 259–547UCSCDynamin central region

GEDaa 569–660UCSCDynamin GTPase effector domain

Gene Aliases

HGNC Name

MX dynamin like GTPase 1

HGNC Alias Symbols

IFI-78K; MxA; lncMX1-215

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002462.5

p.A381G

c.1142C>G

Surrounding Variants

6 papers

NM_002462.5

p.V379I

c.1135G>A

1 paper

NM_002462.5

p.Q384E

c.1150C>G

1 paper

NM_002462.5

p.L389R

c.1166T>G

1 paper

NM_002462.5

p.M390T

c.1169T>C

1 paper

NM_002462.5

p.G392V

c.1175G>T

1 paper

NM_002462.5

p.E394K

c.1180G>A

1 paper

NM_002462.5

p.V396V

c.1188A>C

1 paper

NM_002462.5

p.R402W

c.1204C>T

2 papers

NM_002462.5

p.R402Q

c.1205G>A

1 paper

NM_002462.5

p.L407R

c.1220T>G

1 paper

NM_002462.5

p.R408Q

c.1223G>A

1 paper

NM_002462.5

p.T416A

c.1246A>G