Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.L18F

c.52C>T

Surrounding Variants

1 paper

NM_002467.6

p.L18V

c.52C>G

1 paper

NM_002467.6

p.L18fs

c.52_53fs

1 paper

NM_002467.6

p.P17P

c.51C>G

1 paper

NM_002467.6

p.L18P

c.53T>C

1 paper

NM_002467.6

p.L18R

c.53T>G

1 paper

NM_002467.6

p.P17H

c.50C>A

2 papers

NM_002467.6

p.N19H

c.55A>C

1 paper

NM_002467.6

p.N19Y

c.55A>T

4 papers

NM_002467.6

p.P17S

c.49C>T

1 paper

NM_002467.6

p.N19T

c.56A>C

1 paper

NM_002467.6

p.N19S

c.56A>G

1 paper

NM_002467.6

p.P17insFs

c.50dupC