Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_002467.6

p.S21T

c.62G>C

Surrounding Variants

8 papers

NM_002467.6

p.S21N

c.62G>A

1 paper

NM_002467.6

p.S21_F22insFs

c.63_64ins13

2 papers

NM_002467.6

p.S21I

c.62G>T

4 papers

NM_002467.6

p.S21R

c.61A>C

1 paper

NM_002467.6

p.S21C

c.61A>T

4 papers

NM_002467.6

p.S21R

c.63C>A

1 paper

NM_002467.6

p.F22insFs

c.64_65insT

4 papers

NM_002467.6

p.S21R

c.63C>G

10 papers

NM_002467.6

p.F22L

c.64T>C

1 paper

NM_002467.6

p.V20V

c.60T>G

1 paper

NM_002467.6

p.V20D

c.59T>A

3 papers

NM_002467.6

p.V20A

c.59T>C