Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_002467.6

p.T23S

c.67A>T

Surrounding Variants

10 papers

NM_002467.6

p.F22L

c.66C>A

1 paper

NM_002467.6

p.T23N

c.68C>A

11 papers

NM_002467.6

p.F22L

c.66C>G

1 paper

NM_002467.6

p.T23_N24delins

c.68_71delinsGCAG

1 paper

NM_002467.6

p.T23_N24ins1

c.69_70insATT

1 paper

NM_002467.6

p.N24_R25delFs

c.70_74del5

10 papers

NM_002467.6

p.F22L

c.64T>C

3 papers

NM_002467.6

p.N24S

c.71A>G

4 papers

NM_002467.6

p.S21R

c.63C>A

1 paper

NM_002467.6

p.F22insFs

c.64_65insT

4 papers

NM_002467.6

p.S21R

c.63C>G

2 papers

NM_002467.6

p.N24K

c.72C>A