Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.N26T

c.77A>C

Surrounding Variants

26 papers

NM_002467.6

p.N26S

c.77A>G

1 paper

NM_002467.6

p.N26I

c.77A>T

1 paper

NM_002467.6

p.N26delins

c.77_78delinsGT

2 papers

NM_002467.6

p.N26K

c.78C>A

2 papers

NM_002467.6

p.N26K

c.78C>G

3 papers

NM_002467.6

p.Y27N

c.79T>A

1 paper

NM_002467.6

p.Y27D

c.79T>G

1 paper

NM_002467.6

p.Y27delFs

c.80delA

3 papers

NM_002467.6

p.Y27S

c.80A>C

4 papers

NM_002467.6

p.Y27C

c.80A>G

1 paper

NM_002467.6

p.R25K

c.74G>A

1 paper

NM_002467.6

p.R25G

c.73A>G