Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.P36P

c.108G>C

Surrounding Variants

1 paper

NM_002467.6

p.P36P

c.108G>A

1 paper

NM_002467.6

p.Y37N

c.109T>A

1 paper

NM_002467.6

p.Y37D

c.109T>G

3 papers

NM_002467.6

p.P36S

c.106C>T

1 paper

NM_002467.6

p.Q35Q

c.105G>A

2 papers

NM_002467.6

p.Q35H

c.105G>C

1 paper

NM_002467.6

p.Q35H

c.105G>T

1 paper

NM_002467.6

p.Y37*

c.111T>A

1 paper

NM_002467.6

p.Y37*

c.111T>G

1 paper

NM_002467.6

p.F38_E44delFs

c.112_131del20

2 papers

NM_002467.6

p.Q35L

c.104A>T

1 paper

NM_002467.6

p.F38V

c.112T>G