Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.E42Fs

c.125delinsTTFs

Surrounding Variants

1 paper

NM_002467.6

p.E42G

c.125A>G

1 paper

NM_002467.6

p.E42V

c.125A>T

3 papers

NM_002467.6

p.E42K

c.124G>A

1 paper

NM_002467.6

p.E42E

c.126G>A

1 paper

NM_002467.6

p.E42D

c.126G>C

1 paper

NM_002467.6

p.E42D

c.126G>T

3 papers

NM_002467.6

p.E44del1

c.130_131delGAG

2 papers

NM_002467.6

p.E43K

c.127G>A

1 paper

NM_002467.6

p.E43Q

c.127G>C

1 paper

NM_002467.6

p.E43G

c.128A>G

1 paper

NM_002467.6

p.E43E

c.129G>A

1 paper

NM_002467.6

p.E43D

c.129G>C