Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.F46I

c.136T>A

Surrounding Variants

4 papers

NM_002467.6

p.F46L

c.136T>C

1 paper

NM_002467.6

p.N45K

c.135C>A

1 paper

NM_002467.6

p.N45N

c.135C>T

1 paper

NM_002467.6

p.F46delFs

c.136delT

1 paper

NM_002467.6

p.F46delFs

c.136_137delTT

1 paper

NM_002467.6

p.F46S

c.137T>C

1 paper

NM_002467.6

p.F46_Y47del1

c.137_139delTCT

4 papers

NM_002467.6

p.F46L

c.138C>A

1 paper

NM_002467.6

p.Y47Fs

c.139delinsTTFs

4 papers

NM_002467.6

p.F46L

c.138C>G

1 paper

NM_002467.6

p.Y47H

c.139T>C

1 paper

NM_002467.6

p.E44E

c.132G>A