Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

15 papers

NM_002467.6

p.Q48del1

c.142_143delCAG

Surrounding Variants

1 paper

NM_002467.6

p.Y47*

c.141C>A

2 papers

NM_002467.6

p.Q52ins0

c.154_156dupCAG

1 paper

NM_002467.6

p.Y47*

c.141C>G

2 papers

NM_002467.6

p.Y47Y

c.141C>T

1 paper

NM_002467.6

p.Q48fs

c.142_143fs

1 paper

NM_002467.6

p.Q48insFs

c.143_144insC

1 paper

NM_002467.6

p.Q48P

c.143A>C

1 paper

NM_002467.6

p.Q48L

c.143A>T

1 paper

NM_002467.6

p.Y47H

c.139T>C

4 papers

NM_002467.6

p.F46L

c.138C>A

1 paper

NM_002467.6

p.Y47Fs

c.139delinsTTFs

4 papers

NM_002467.6

p.F46L

c.138C>G