Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.Q49R

c.146A>G

Surrounding Variants

1 paper

NM_002467.6

p.Q49insFs

c.146_147insC

4 papers

NM_002467.6

p.Q49L

c.146A>T

1 paper

NM_002467.6

p.Q49K

c.145C>A

1 paper

NM_002467.6

p.Q49fs

c.145_146fs

1 paper

NM_002467.6

p.Q49Q

c.147G>A

2 papers

NM_002467.6

p.Q49H

c.147G>C

2 papers

NM_002467.6

p.Q49H

c.147G>T

1 paper

NM_002467.6

p.Q50*

c.148C>T

3 papers

NM_002467.6

p.Q48Q

c.144G>A

12 papers

NM_002467.6

p.Q48H

c.144G>C

12 papers

NM_002467.6

p.Q48H

c.144G>T

1 paper

NM_002467.6

p.Q48insFs

c.143_144insC