Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.S53T

c.158G>C

Surrounding Variants

1 paper

NM_002467.6

p.S53N

c.158G>A

1 paper

NM_002467.6

p.S53insFs

c.158_159insTA

1 paper

NM_002467.6

p.S53I

c.158G>T

1 paper

NM_002467.6

p.S53G

c.157A>G

2 papers

NM_002467.6

p.E54Q

c.160G>C

1 paper

NM_002467.6

p.E54fs

c.160_161fs

1 paper

NM_002467.6

p.E54A

c.161A>C

1 paper

NM_002467.6

p.Q52R

c.155A>G

2 papers

NM_002467.6

p.E54V

c.161A>T

1 paper

NM_002467.6

p.Q52K

c.154C>A

1 paper

NM_002467.6

p.Q52insFs

c.155_156insTA

1 paper

NM_002467.6

p.Q52E

c.154C>G