Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

20 papers

NM_002467.6

p.P72S

c.214C>T

Surrounding Variants

12 papers

NM_002467.6

p.P72T

c.214C>A

1 paper

NM_002467.6

p.P72fs

c.214_215fs

6 papers

NM_002467.6

p.P72A

c.214C>G

3 papers

NM_002467.6

p.P72H

c.215C>A

3 papers

NM_002467.6

p.P72R

c.215C>G

3 papers

NM_002467.6

p.P72L

c.215C>T

1 paper

NM_002467.6

p.L71L

c.213G>A

1 paper

NM_002467.6

p.L71_P72insFs

c.213_214insT

1 paper

NM_002467.6

p.L71L

c.213G>T

2 papers

NM_002467.6

p.L71_P72delins

c.213_215delinsTAA

1 paper

NM_002467.6

p.P72P

c.216C>T

2 papers

NM_002467.6

p.L71P

c.212T>C