Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.T73_P74delins

c.217_221delinsGGGTT

Surrounding Variants

5 papers

NM_002467.6

p.T73P

c.217A>C

16 papers

NM_002467.6

p.T73A

c.217A>G

1 paper

NM_002467.6

p.T73S

c.217A>T

14 papers

NM_002467.6

p.T73N

c.218C>A

1 paper

NM_002467.6

p.T73S

c.218C>G

21 papers

NM_002467.6

p.T73I

c.218C>T

1 paper

NM_002467.6

p.P72P

c.216C>T

1 paper

NM_002467.6

p.T73delins

c.218_219delinsTA

1 paper

NM_002467.6

p.T73delins

c.218_219delinsTT

3 papers

NM_002467.6

p.P72H

c.215C>A

1 paper

NM_002467.6

p.T73_P74insFs

c.219_220insG

3 papers

NM_002467.6

p.P72R

c.215C>G