Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.P75H

c.224C>A

Surrounding Variants

1 paper

NM_002467.6

p.P75_L76ins0

c.225_227dupCCT

6 papers

NM_002467.6

p.P75L

c.224C>T

3 papers

NM_002467.6

p.P75T

c.223C>A

1 paper

NM_002467.6

p.P75P

c.225C>A

6 papers

NM_002467.6

p.P75A

c.223C>G

5 papers

NM_002467.6

p.P75S

c.223C>T

1 paper

NM_002467.6

p.L76V

c.226C>G

1 paper

NM_002467.6

p.L76_S79delFs

c.227_236del10

1 paper

NM_002467.6

p.L76_V90del0

c.228_269del42

1 paper

NM_002467.6

p.P75_L76delFs

c.223_227del5

8 papers

NM_002467.6

p.P74Q

c.221C>A

3 papers

NM_002467.6

p.P74R

c.221C>G