Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.P78H

c.233C>A

Surrounding Variants

1 paper

NM_002467.6

p.P78T

c.232C>A

3 papers

NM_002467.6

p.P78A

c.232C>G

2 papers

NM_002467.6

p.P78S

c.232C>T

2 papers

NM_002467.6

p.P78P

c.234T>A

3 papers

NM_002467.6

p.S79R

c.235A>C

1 paper

NM_002467.6

p.S79G

c.235A>G

1 paper

NM_002467.6

p.S77S

c.231C>T

1 paper

NM_002467.6

p.S77Y

c.230C>A

7 papers

NM_002467.6

p.S77F

c.230C>T

2 papers

NM_002467.6

p.S79N

c.236G>A

1 paper

NM_002467.6

p.S79_V92insFs

c.237_276dup40

2 papers

NM_002467.6

p.S79R

c.237C>A