Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

14 papers

NM_002467.6

p.L84F

c.250C>T

Surrounding Variants

1 paper

NM_002467.6

p.L84_P87del4

c.250_260del12

2 papers

NM_002467.6

p.L84P

c.251T>C

1 paper

NM_002467.6

p.G83E

c.248G>A

1 paper

NM_002467.6

p.G83_L84delFs

c.248_252del5

2 papers

NM_002467.6

p.C85Y

c.254G>A

1 paper

NM_002467.6

p.S82Y

c.245C>A

2 papers

NM_002467.6

p.S82C

c.245C>G

1 paper

NM_002467.6

p.C85W

c.255C>G

1 paper

NM_002467.6

p.S82delins

c.245_246delinsTA

3 papers

NM_002467.6

p.S82T

c.244T>A

1 paper

NM_002467.6

p.S86L

c.257C>T

1 paper

NM_002467.6

p.R81H

c.242G>A