Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002467.6

p.Y89N

c.265T>A

Surrounding Variants

1 paper

NM_002467.6

p.Y89C

c.266A>G

1 paper

NM_002467.6

p.Y89F

c.266A>T

1 paper

NM_002467.6

p.V90_A91delFs

c.269_273del5

1 paper

NM_002467.6

p.S88S

c.264C>A

1 paper

NM_002467.6

p.Y89insFs

c.265dupT

2 papers

NM_002467.6

p.S88S

c.264C>T

2 papers

NM_002467.6

p.S88Y

c.263C>A

3 papers

NM_002467.6

p.S88F

c.263C>T

2 papers

NM_002467.6

p.Y89Y

c.267C>T

1 paper

NM_002467.6

p.V90I

c.268G>A

1 paper

NM_002467.6

p.S88A

c.262T>G

1 paper

NM_002467.6

p.P87P

c.261C>A