Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.S109T

c.325T>A

Surrounding Variants

1 paper

NM_002467.6

p.S109Y

c.326C>A

1 paper

NM_002467.6

p.S109S

c.327C>A

1 paper

NM_002467.6

p.F108V

c.322T>G

1 paper

NM_002467.6

p.S107R

c.321C>A

2 papers

NM_002467.6

p.S107R

c.321C>G

1 paper

NM_002467.6

p.T110M

c.329C>T

2 papers

NM_002467.6

p.T110T

c.330G>A

1 paper

NM_002467.6

p.S107N

c.320G>A

2 papers

NM_002467.6

p.S107T

c.320G>C

1 paper

NM_002467.6

p.T110T

c.330G>C

1 paper

NM_002467.6

p.S107R

c.319A>C

1 paper

NM_002467.6

p.A111insFs

c.333dupC