Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.V126_S129delins

c.378_385delinsGA

Surrounding Variants

1 paper

NM_002467.6

p.V126E

c.377T>A

1 paper

NM_002467.6

p.V126M

c.376G>A

1 paper

NM_002467.6

p.N127D

c.379A>G

1 paper

NM_002467.6

p.M125I

c.375G>A

1 paper

NM_002467.6

p.N127I

c.380A>T

1 paper

NM_002467.6

p.N127K

c.381C>A

1 paper

NM_002467.6

p.N127K

c.381C>G

2 papers

NM_002467.6

p.Q128E

c.382C>G

1 paper

NM_002467.6

p.D124D

c.372C>T

1 paper

NM_002467.6

p.D124G

c.371A>G

1 paper

NM_002467.6

p.D124V

c.371A>T

1 paper

NM_002467.6

p.Q128L

c.383A>T