Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002467.6

p.C132S

c.394T>A

Surrounding Variants

1 paper

NM_002467.6

p.C132R

c.394T>C

1 paper

NM_002467.6

p.I131I

c.393C>T

2 papers

NM_002467.6

p.C132S

c.395G>C

1 paper

NM_002467.6

p.C132*

c.396C>A

2 papers

NM_002467.6

p.C132W

c.396C>G

1 paper

NM_002467.6

p.I131T

c.392T>C

1 paper

NM_002467.6

p.D133N

c.397G>A

2 papers

NM_002467.6

p.D133A

c.398A>C

1 paper

NM_002467.6

p.D133E

c.399C>A

1 paper

NM_002467.6

p.D133D

c.399C>T

2 papers

NM_002467.6

p.F130C

c.389T>G

1 paper

NM_002467.6

p.P134_F139Fs

c.400_417delinsAFs