Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.E137D

c.411G>T

Surrounding Variants

1 paper

NM_002467.6

p.E137D

c.411G>C

1 paper

NM_002467.6

p.T138_I144del0

c.412_432del21

1 paper

NM_002467.6

p.E137_T138ins3

c.411_412ins9

2 papers

NM_002467.6

p.E137G

c.410A>G

1 paper

NM_002467.6

p.E137V

c.410A>T

2 papers

NM_002467.6

p.E137Q

c.409G>C

1 paper

NM_002467.6

p.T138T

c.414C>G

1 paper

NM_002467.6

p.D136A

c.407A>C

2 papers

NM_002467.6

p.F139L

c.415T>C

2 papers

NM_002467.6

p.D136delins

c.406_407delinsTG

1 paper

NM_002467.6

p.F139Y

c.416T>A

1 paper

NM_002467.6

p.F139S

c.416T>C