Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.I145F

c.433A>T

Surrounding Variants

1 paper

NM_002467.6

p.I145T

c.434T>C

1 paper

NM_002467.6

p.Q146_D147insC

c.436_440ins3

1 paper

NM_002467.6

p.Q146Q

c.438G>A

2 papers

NM_002467.6

p.Q146H

c.438G>C

2 papers

NM_002467.6

p.Q146H

c.438G>T

1 paper

NM_002467.6

p.I143_I144insC

c.427_431ins3

1 paper

NM_002467.6

p.I143L

c.427A>C

1 paper

NM_002467.6

p.I143V

c.427A>G

1 paper

NM_002467.6

p.N142K

c.426C>A

1 paper

NM_002467.6

p.N142K

c.426C>G

1 paper

NM_002467.6

p.N142S

c.425A>G

1 paper

NM_002467.6

p.K141K

c.423A>G