Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002467.6

p.K158E

c.472A>G

Surrounding Variants

1 paper

NM_002467.6

p.K158_L159insTA

c.472_476ins6

1 paper

NM_002467.6

p.K158*

c.472A>T

1 paper

NM_002467.6

p.K158_V160ins1

c.472_480dup9

1 paper

NM_002467.6

p.A157V

c.470C>T

3 papers

NM_002467.6

p.K158K

c.474G>A

7 papers

NM_002467.6

p.A157T

c.469G>A

1 paper

NM_002467.6

p.A157P

c.469G>C

1 paper

NM_002467.6

p.A157S

c.469G>T

1 paper

NM_002467.6

p.A156A

c.468C>T

1 paper

NM_002467.6

p.L159L

c.477C>G

3 papers

NM_002467.6

p.A156T

c.466G>A

2 papers

NM_002467.6

p.V160I

c.478G>A