Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002467.6

p.V160I

c.478G>A

Surrounding Variants

3 papers

NM_002467.6

p.V160L

c.478G>C

1 paper

NM_002467.6

p.L159L

c.477C>G

1 paper

NM_002467.6

p.S161A

c.481T>G

1 paper

NM_002467.6

p.S161*

c.482C>A

33 papers

NM_002467.6

p.S161L

c.482C>T

3 papers

NM_002467.6

p.K158K

c.474G>A

1 paper

NM_002467.6

p.S161S

c.483A>G

1 paper

NM_002467.6

p.K158_L159insTA

c.472_476ins6

2 papers

NM_002467.6

p.K158E

c.472A>G

1 paper

NM_002467.6

p.K158*

c.472A>T

1 paper

NM_002467.6

p.E162_S166del0

c.485_496del12

1 paper

NM_002467.6

p.E162G

c.485A>G