Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.R171C

c.511C>T

Surrounding Variants

2 papers

NM_002467.6

p.R171G

c.511C>G

1 paper

NM_002467.6

p.R171H

c.512G>A

1 paper

NM_002467.6

p.R171L

c.512G>T

2 papers

NM_002467.6

p.A170V

c.509C>T

1 paper

NM_002467.6

p.A170T

c.508G>A

1 paper

NM_002467.6

p.A169V

c.506C>T

1 paper

NM_002467.6

p.A169T

c.505G>A

1 paper

NM_002467.6

p.A169P

c.505G>C

1 paper

NM_002467.6

p.A169S

c.505G>T

1 paper

NM_002467.6

p.D173delFs

c.518delA

2 papers

NM_002467.6

p.D173A

c.518A>C

1 paper

NM_002467.6

p.D173G

c.518A>G