Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_002467.6

p.G175D

c.524G>A

Surrounding Variants

1 paper

NM_002467.6

p.G175A

c.524G>C

2 papers

NM_002467.6

p.G175C

c.523G>T

1 paper

NM_002467.6

p.G175delins

c.523_524delinsAC

1 paper

NM_002467.6

p.S174S

c.522C>T

1 paper

NM_002467.6

p.S174N

c.521G>A

1 paper

NM_002467.6

p.S174T

c.521G>C

1 paper

NM_002467.6

p.S176I

c.527G>T

1 paper

NM_002467.6

p.S174fs

c.520_521fs

1 paper

NM_002467.6

p.S176R

c.528C>G

1 paper

NM_002467.6

p.D173D

c.519C>T

2 papers

NM_002467.6

p.D173A

c.518A>C

1 paper

NM_002467.6

p.D173G

c.518A>G