Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.C186S

c.557G>C

Surrounding Variants

2 papers

NM_002467.6

p.C186Y

c.557G>A

1 paper

NM_002467.6

p.C186S

c.556T>A

1 paper

NM_002467.6

p.S187C

c.560C>G

2 papers

NM_002467.6

p.S187F

c.560C>T

2 papers

NM_002467.6

p.V185D

c.554T>A

1 paper

NM_002467.6

p.V185A

c.554T>C

1 paper

NM_002467.6

p.S187S

c.561C>A

5 papers

NM_002467.6

p.V185I

c.553G>A

1 paper

NM_002467.6

p.T188_L196del0

c.563_586del24

1 paper

NM_002467.6

p.S184R

c.552C>A

1 paper

NM_002467.6

p.S184R

c.552C>G

1 paper

NM_002467.6

p.T188I

c.563C>T