Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.L193L

c.577C>T

Surrounding Variants

2 papers

NM_002467.6

p.L193_Q194delins

c.579_580delinsTG

2 papers

NM_002467.6

p.Q194E

c.580C>G

1 paper

NM_002467.6

p.Y192N

c.574T>A

1 paper

NM_002467.6

p.Y192insFs

c.575_576insA

1 paper

NM_002467.6

p.L191L

c.573G>A

2 papers

NM_002467.6

p.L191F

c.573G>C

2 papers

NM_002467.6

p.L191F

c.573G>T

1 paper

NM_002467.6

p.D195N

c.583G>A

1 paper

NM_002467.6

p.L191L

c.571T>C

2 papers

NM_002467.6

p.D195A

c.584A>C

5 papers

NM_002467.6

p.S190R

c.570C>A

5 papers

NM_002467.6

p.S190R

c.570C>G