Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_002467.6

p.S207L

c.620C>T

Surrounding Variants

1 paper

NM_002467.6

p.V208_S222del15

c.622_665del45

1 paper

NM_002467.6

p.S207P

c.619T>C

1 paper

NM_002467.6

p.V208M

c.622G>A

1 paper

NM_002467.6

p.P206A

c.616C>G

1 paper

NM_002467.6

p.V208_V209delins

c.624_625delinsTG

2 papers

NM_002467.6

p.D205G

c.614A>G

2 papers

NM_002467.6

p.V209D

c.626T>A

1 paper

NM_002467.6

p.D205N

c.613G>A

1 paper

NM_002467.6

p.F210insFs

c.628_629insA

1 paper

NM_002467.6

p.I204N

c.611T>A

1 paper

NM_002467.6

p.I204T

c.611T>C

3 papers

NM_002467.6

p.F210C

c.629T>G