Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.L214_S228del15

c.640_683del45

Surrounding Variants

1 paper

NM_002467.6

p.P213R

c.638C>G

1 paper

NM_002467.6

p.L214V

c.640C>G

1 paper

NM_002467.6

p.P213L

c.638C>T

1 paper

NM_002467.6

p.P213_L214insT

c.637_641ins3

1 paper

NM_002467.6

p.P213_L214insATG

c.637_641ins9

2 papers

NM_002467.6

p.P213S

c.637C>T

1 paper

NM_002467.6

p.Y212*

c.636C>G

2 papers

NM_002467.6

p.Y212C

c.635A>G

1 paper

NM_002467.6

p.Y212F

c.635A>T

1 paper

NM_002467.6

p.N215T

c.644A>C

2 papers

NM_002467.6

p.Y212N

c.634T>A

2 papers

NM_002467.6

p.D216N

c.646G>A