Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.C223_D227del5

c.667_680del15

Surrounding Variants

1 paper

NM_002467.6

p.S222C

c.665C>G

1 paper

NM_002467.6

p.S222F

c.665C>T

1 paper

NM_002467.6

p.S222A

c.664T>G

1 paper

NM_002467.6

p.K221N

c.663G>T

1 paper

NM_002467.6

p.C223R

c.667T>C

2 papers

NM_002467.6

p.C223G

c.667T>G

1 paper

NM_002467.6

p.A224T

c.670G>A

2 papers

NM_002467.6

p.A224V

c.671C>T

1 paper

NM_002467.6

p.P220A

c.658C>G

1 paper

NM_002467.6

p.P220del1

c.658_660delCCC

2 papers

NM_002467.6

p.S219L

c.656C>T

2 papers

NM_002467.6

p.S225L

c.674C>T