Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.S228P

c.682T>C

Surrounding Variants

1 paper

NM_002467.6

p.S228delFs

c.684delC

1 paper

NM_002467.6

p.D227E

c.681C>A

1 paper

NM_002467.6

p.D227E

c.681C>G

1 paper

NM_002467.6

p.S229del1

c.685_686delAGC

1 paper

NM_002467.6

p.D227A

c.680A>C

1 paper

NM_002467.6

p.S229R

c.685A>C

3 papers

NM_002467.6

p.D227N

c.679G>A

2 papers

NM_002467.6

p.D227_S229del0

c.680_685del6

1 paper

NM_002467.6

p.Q226H

c.678A>C

2 papers

NM_002467.6

p.Q226H

c.678A>T

2 papers

NM_002467.6

p.S229N

c.686G>A

1 paper

NM_002467.6

p.Q226R

c.677A>G