Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002467.6

p.A230V

c.689C>T

Surrounding Variants

2 papers

NM_002467.6

p.A230T

c.688G>A

1 paper

NM_002467.6

p.A230S

c.688G>T

2 papers

NM_002467.6

p.F231L

c.691T>C

2 papers

NM_002467.6

p.S229N

c.686G>A

1 paper

NM_002467.6

p.S229R

c.685A>C

1 paper

NM_002467.6

p.F231L

c.693C>A

1 paper

NM_002467.6

p.F231L

c.693C>G

1 paper

NM_002467.6

p.S232P

c.694T>C

1 paper

NM_002467.6

p.S232C

c.695C>G

1 paper

NM_002467.6

p.S232F

c.695C>T

1 paper

NM_002467.6

p.S229del1

c.685_686delAGC

1 paper

NM_002467.6

p.S228P

c.682T>C