Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002467.6

p.D236N

c.706G>A

Surrounding Variants

2 papers

NM_002467.6

p.D236delins

c.706_707delinsTG

1 paper

NM_002467.6

p.D236G

c.707A>G

2 papers

NM_002467.6

p.S235L

c.704C>T

1 paper

NM_002467.6

p.S237C

c.710C>G

1 paper

NM_002467.6

p.S237F

c.710C>T

1 paper

NM_002467.6

p.S234F

c.701C>T

1 paper

NM_002467.6

p.L238M

c.712C>A

1 paper

NM_002467.6

p.L238V

c.712C>G

1 paper

NM_002467.6

p.S234T

c.700T>A

1 paper

NM_002467.6

p.S234P

c.700T>C

2 papers

NM_002467.6

p.L238R

c.713T>G

1 paper

NM_002467.6

p.P233Q

c.698C>A